Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.54 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.45 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503550 | 0.97 | TLR8 (0.54) | TLR8NCF1MCHR1CSNK1A1CSNK1D | |
| SCHEMBL28906706 | 0.95 | TLR8 (0.54) | TLR8NCF1MCHR1CSNK1A1CSNK1D | |
| SCHEMBL28504818 | 0.90 | TLR8 (0.51) | TLR8TLR7LMNATSHR | |
| SCHEMBL29377718 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHR | |
| SCHEMBL28203089 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHR | |
| SCHEMBL22498767 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHR | |
| SCHEMBL1458588 | 0.88 | TLR8 (0.57) | TLR8TLR7LMNATSHR | |
| SCHEMBL28508187 | 0.87 | TLR8 (0.48) | TLR8TLR7LMNATSHR | |
| SCHEMBL28508378 | 0.80 | CYP1A2 (0.52) | NCF1TLR7LMNATSHRCYP1A2 | |
| SCHEMBL28514142 | 0.78 | LMNA (0.52) | TLR8LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |