Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504818 | 0.97 | TLR8 (0.51) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL22498767 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL28203089 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL29377718 | 0.89 | TLR8 (0.58) | TLR8TLR7LMNATSHRKDM4E | |
| SCHEMBL1458588 | 0.87 | TLR8 (0.57) | TLR8TLR7LMNATSHR | |
| SCHEMBL28510573 | 0.87 | TLR8 (0.54) | TLR8TLR7LMNATSHR | |
| SCHEMBL28503550 | 0.85 | TLR8 (0.54) | TLR8TLR7LMNACYP3A4MAPT | |
| SCHEMBL28508378 | 0.82 | CYP1A2 (0.52) | TLR7LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL28906706 | 0.82 | TLR8 (0.54) | TLR8TLR7LMNACYP3A4MAPT | |
| SCHEMBL28229720 | 0.80 | KDM4E (0.55) | TLR8TLR7KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250142-B | Amine compounds having anti-inflammatory, antifungal, antiparasitic and anticancer activity | 维尔斯达医疗公司 | 2021-01-26 | — | — | CN | disclosed |