Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.35 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823700 | 0.86 | PPARG (0.39) | ACACBPPARGPPARAKMT2APTPN1 | |
| SCHEMBL18301502 | 0.83 | KMT2A (0.40) | PPARGPPARAKMT2APTPN1FABP5 | |
| SCHEMBL8064068 | 0.82 | DPP4 (0.41) | KMT2APTPN1FABP5FABP7EPHX2 | |
| SCHEMBL599716 | 0.81 | EPHX2 (0.38) | KMT2AEPHX2CA1CA2 | |
| SCHEMBL18986722 | 0.81 | EPHX2 (0.42) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL598210 | 0.80 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL8933068 | 0.80 | PTPN1 (0.54) | KMT2APTPN1 | |
| SCHEMBL16080167 | 0.78 | PTPN1 (0.49) | PTPN1 | |
| SCHEMBL16075059 | 0.78 | PTPN1 (0.49) | PTPN1 | |
| SCHEMBL11067134 | 0.78 | ACACB (0.49) | ACACBPPARGPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858091-B2 | Antibodies to insulin-like growth factor binding protein and uses thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| EP-2077275-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2009-07-08 | — | — | EP | disclosed |
| US-20080241960-A1 | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1975175-A2 | IgA nephropathy-related DNA | Nihon University (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-7332301-B2 | Insulin-like growth factor binding protein | KYOWA HAAKKO KOGYO CO. LTD. (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20060216739-A1 | Insulin-like growth factor binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7071160-B2 | Insulin-like growth factor-binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-6962984-B2 | DNA whose expression level fluctuates in leukocytes of IgA nephropathy patients in comparison with leukocytes of healthy persons, a process for isolating the DNA, a novel protein encoded by the DNA, an antibody recognizing the protein, | NIHON UNIVERSITY (JP) | 2005-11-08 | — | — | US | disclosed |
| US-20050137138-A1 | E2F activity-inhibiting compound | KYOWA HAKKO KOGYO CO., LTD (JP) | 2005-06-23 | — | — | US | disclosed |
| US-20040072238-A1 | Insulin-like growth factor-binding protein | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1085090-A1 | IgA NEPHROPATHY-ASSOCIATED DNA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6194195-B1 | PURE CULTURE; FOR PRODUCTION OF HYPOTENSIVE AGENTS AND THERAPIES FOR ASTHMA, CEREBRAL APOPLEXY, ANGINA PECTORIS, ACUTE RENAL FAILURE, CARDIAC INFARCTION, AND CEREBRAL VASOSPASM | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0963999-A1 | E2F ACTIVITY INHIBITORY COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0922710-A1 | PEPTIDES PROMOTING THE ACTIVATION OF LATENT TGF-$g(b) AND METHOD FOR SCREENING TGF-$g(b) ACTIVITY REGULATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-06-16 | — | — | EP | disclosed |
| EP-0672679-B1 | PHOSPHOLIPASE C INHIBITING PEPTIDE | KYOWA HAKKO KOGYO KK (JP) | 1998-01-28 | — | — | EP | disclosed |
| EP-0770623-A1 | NOVEL CALCITONIN DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| EP-0760376-A1 | PEPTIDES INHIBITING PHOSPHOLIPASE C | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0679658-A1 | ENDOTHELIN-ANTAGONIZING PEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0672679-A1 | PHOSPHOLIPASE C INHIBITING PEPTIDE | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1995-09-20 | — | — | EP | disclosed |
| EP-0672680-A1 | NOVEL PEPTIDE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-09-20 | — | — | EP | disclosed |