Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 5/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | PTPRB | P23467 | 3/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301502 | 0.90 | KMT2A (0.40) | PTPN1KMT2A | |
| SCHEMBL2820518 | 0.80 | ACACB (0.40) | PTPN1KMT2A | |
| SCHEMBL18986722 | 0.79 | EPHX2 (0.42) | KMT2A | |
| SCHEMBL8064068 | 0.78 | DPP4 (0.41) | PTPN1KMT2A | |
| SCHEMBL8933064 | 0.77 | MDM2 (0.52) | PTPN1 | |
| SCHEMBL20815735 | 0.76 | PTPN1 (0.47) | PTPN1KMT2A | |
| SCHEMBL599716 | 0.76 | EPHX2 (0.38) | KMT2A | |
| SCHEMBL9359183 | 0.73 | ALDH1A1 (0.44) | PTPN1KMT2A | |
| SCHEMBL7369838 | 0.72 | KMT2A (0.41) | KMT2A | |
| SCHEMBL8035578 | 0.72 | KMT2A (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023813-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO SH2 DOMAINS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-08-08 | — | — | WO | disclosed |