Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18986722 | 0.87 | EPHX2 (0.42) | EPHX2KMT2ACA1CA2CASP3 | |
| SCHEMBL2820518 | 0.81 | ACACB (0.40) | EPHX2KMT2ACA1CA2 | |
| SCHEMBL29599644 | 0.79 | MDM2 (0.49) | MDM2ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL29402071 | 0.79 | MDM2 (0.49) | MDM2ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL18301502 | 0.79 | KMT2A (0.40) | EPHX2KMT2AMDM2CA1CA2 | |
| SCHEMBL15160752 | 0.78 | EPHX2 (0.54) | EPHX2KMT2AMDM2CA12CA1 | |
| SCHEMBL15160753 | 0.78 | EPHX2 (0.54) | EPHX2KMT2AMDM2CA12CA1 | |
| SCHEMBL8064068 | 0.78 | DPP4 (0.41) | EPHX2KMT2ACA1CA2 | |
| SCHEMBL8933068 | 0.76 | PTPN1 (0.54) | KMT2A | |
| SCHEMBL21683110 | 0.76 | EPHX2 (0.47) | EPHX2KMT2AMDM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332495-B2 | Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix | RK Pharma Solutions LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210094984-A1 | Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix | CITIBANK, N.A. | 2021-04-01 | — | — | US | disclosed |
| EP-2421887-B1 | METHOD FOR THE MANUFACTURE OF DEGARELIX | POLYPEPTIDE LABORATORIES AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| US-8828938-B2 | Method for the manufacture of degarelix | POLYPEPTIDE LABORATORIES A/S (DK) | 2014-09-09 | — | — | US | disclosed |
| US-20120041172-A1 | METHOD FOR THE MANUFACTURE OF DEGARELIX | POLYPEPTIDE LABORATORIES A/S (DK) | 2012-02-16 | — | — | US | disclosed |
| WO-2010121835-A1 | METHOD FOR THE MANUFACTURE OF DEGARELIX | POLYPEPTIDE LABORATORIES A/S (DK) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332495-B2 | Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix | PEPD, DNPEP, PREP | EPHX2 3090/4885KMT2A 2862/4885MEN1 138/4885 |
| US-20210094984-A1 | Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix | PEPD, DNPEP, PREP | EPHX2 3098/4885KMT2A 2874/4885MEN1 140/4885 |
| US-20120041172-A1 | METHOD FOR THE MANUFACTURE OF DEGARELIX | DNPEP, PEPD, VIP | EPHX2 1296/4885KMT2A 1270/4885MEN1 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.