Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933068 | 0.90 | PTPN1 (0.54) | KMT2APTPN1 | |
| SCHEMBL2820518 | 0.83 | ACACB (0.40) | KMT2APTPN1PPARGPPARAFABP7 | |
| SCHEMBL18986722 | 0.83 | EPHX2 (0.42) | KMT2AFABP7FABP5EPHX2CA1 | |
| SCHEMBL8064068 | 0.81 | DPP4 (0.41) | KMT2APTPN1DPP4FABP7FABP5 | |
| SCHEMBL2311742 | 0.80 | MDM2 (0.43) | KMT2AMDM2PTPN1GRB2PPARG | |
| SCHEMBL2358897 | 0.80 | MDM2 (0.43) | KMT2AMDM2PTPN1GRB2PPARG | |
| SCHEMBL599716 | 0.79 | EPHX2 (0.38) | KMT2AMDM2GRB2EPHX2CA1 | |
| SCHEMBL7369838 | 0.78 | KMT2A (0.41) | KMT2ADPP4DPP8DPP9FABP7 | |
| SCHEMBL9359183 | 0.76 | ALDH1A1 (0.44) | KMT2APTPN1FABP7FABP5EPHX2 | |
| SCHEMBL8035578 | 0.76 | KMT2A (0.41) | KMT2AFABP7FABP5EPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303367-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | New York University (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016201007-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY (US) | 2016-12-15 | — | — | WO | disclosed |