SCHEMBL28205347

SCHEMBL28205347

O=C(O)c1ccccc1C(Cc1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
EPHX1 P07099 1/20 0.47
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 1/20 0.45
ACP3 P15309 1/20 0.43
ALPI P09923 1/20 0.43
PKM P14618 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
SLC7A5 Q01650 1/20 0.43
MAPT P10636 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
ALPL P05186 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906291 0.89 SLC6A3 (0.56) ALDH1A1KMT2AGAATDP1SLC6A2
SCHEMBL5428376 0.81 ALDH1A1 (0.51) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL27935564 0.80 HTR2A (0.54) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL8944151 0.80 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1CYP1A2
SCHEMBL7204826 0.79 NPC1 (0.51) ALDH1A1KMT2AGAATDP1CYP1A2
SCHEMBL8894583 0.79 ALPI (0.52) ALDH1A1KMT2AGAATDP1EPHX1
SCHEMBL9615383 0.78 PTPN1 (0.43) EPHX1SLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL16824139 0.77 ALDH1A1 (0.47) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL7197326 0.77 CAPN1 (0.44) ALDH1A1KMT2AGAATDP1EPHX1
SCHEMBL28997880 0.76 KMT2A (0.46) ALDH1A1KMT2AGAATDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107699917-B A kind of method of electrochemistry formated lactone 南阳师范学院 2019-02-15 CN disclosed
CN-107699917-A A kind of method of electrochemistry formated lactone 南阳师范学院 2018-02-16 CN disclosed