SCHEMBL28207016

SCHEMBL28207016

Cn1c(N)cc(=O)[nH]c1=S.[Zn]

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
KMT2A Q03164 5/20 0.49
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
GAA P10253 3/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 3/20 0.39
CYP3A4 P08684 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.38
LPO P22079 1/20 0.36
PTGS1 P23219 1/20 0.36
MAPT P10636 2/20 0.36
LGMN Q99538 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28298685 0.98 ALDH1A1 (0.50) ALDH1A1KMT2AMTNR1AMTNR1BGAA
SCHEMBL28008497 0.81 KMT2A (0.47) ALDH1A1KMT2AMTNR1AMTNR1BL3MBTL1
SCHEMBL31137 0.79 KMT2A (0.49) ALDH1A1KMT2AMTNR1AMTNR1BL3MBTL1
SCHEMBL19464477 0.75 ALDH1A1 (0.53) ALDH1A1KMT2AGAAMEN1SMN1; SMN2
SCHEMBL1958327 0.73 MTNR1A (0.52) ALDH1A1KMT2AMTNR1AMTNR1BGAA
SCHEMBL28143900 0.72 POLB (0.39) ALDH1A1KMT2AMTNR1AMTNR1BMEN1
SCHEMBL562714 0.71 MTNR1A (0.57) ALDH1A1KMT2AMTNR1AMTNR1BGAA
SCHEMBL1958324 0.71 GAA (0.59) ALDH1A1KMT2AMTNR1AMTNR1BGAA
SCHEMBL7187029 0.70 MTNR1A (0.56) ALDH1A1KMT2AMTNR1AMTNR1BGAA
SCHEMBL7188435 0.70 MTNR1A (0.56) ALDH1A1KMT2AMTNR1AMTNR1BGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104877179-B A kind of organic composite heat stabilizer and preparation method thereof 杭州鸿雁管道系统科技有限公司 2018-02-23 CN claimed