Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 8/20 | 0.62 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.62 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040903 | 0.88 | FEN1 (0.54) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL28207188 | 0.82 | ALOX5AP (0.46) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL18045627 | 0.80 | FEN1 (0.44) | FEN1ALOX5APNPC1RAB9APARP1 | |
| SCHEMBL2113823 | 0.78 | NPC1 (0.59) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL920340 | 0.78 | FEN1 (0.60) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL15916075 | 0.77 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL21590306 | 0.76 | BCAT2 (0.58) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL5878337 | 0.76 | BCAT2 (0.87) | FEN1ALOX5APBCAT2NPC1RAB9A | |
| SCHEMBL30810190 | 0.76 | BCAT2 (0.53) | FEN1ALOX5APBCAT2PARP1CSNK1A1 | |
| SCHEMBL2567641 | 0.75 | BCAT2 (0.71) | FEN1ALOX5APBCAT2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-B | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | disclosed |