Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 5/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207103 | 0.88 | FEN1 (0.62) | FEN1ALOX5APNPC1RAB9AHPGDS | |
| SCHEMBL28192026 | 0.83 | AR (0.53) | FEN1ALOX5APNPC1RAB9AHPGDS | |
| SCHEMBL28191251 | 0.82 | ALOX5AP (0.49) | FEN1ALOX5APWNT3A | |
| SCHEMBL18045627 | 0.75 | FEN1 (0.44) | FEN1ALOX5APNPC1RAB9AHPGDS | |
| SCHEMBL29400809 | 0.74 | BCAT2 (0.47) | FEN1ALOX5APNPC1RAB9ACHEK2 | |
| SCHEMBL16098914 | 0.74 | WNT3A (0.60) | WNT3A | |
| SCHEMBL3265708 | 0.73 | BCAT2 (0.63) | NPC1RAB9ACHEK2MKNK1DHODH | |
| SCHEMBL27898313 | 0.73 | IKBKB (0.48) | CHEK2MKNK1BCAT2ALDH1A1 | |
| SCHEMBL18045625 | 0.72 | WNT3A (0.50) | NPC1RAB9AWNT3ADHODHALDH1A1 | |
| SCHEMBL2070102 | 0.72 | LDHA (0.62) | NPC1RAB9ADHODHALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |