Sugi Predict

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Dimethylformamide

Dimethylformamide

SCHEMBL28207129

CCOCCOCC.CN(C)C=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.42
▸ THRB P10828 1/20 0.37
▸ ALOX15 P16050 1/20 0.36
▸ THRA P10827 1/20 0.33
▸ HTT P42858 1/20 0.31
▸ CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL10802383 0.97 TSHR (0.47) TSHRALDH1A1THRBALOX15THRA
Ether SCHEMBL4609718 0.88 TSHR (0.56) TSHRALDH1A1ALOX15
Ether SCHEMBL335388 0.88 TSHR (0.56) TSHRALDH1A1ALOX15
Diethylene Glycol Monoethyl Ether SCHEMBL10007009 0.87 ALDH1A1 (0.58) TSHRALDH1A1THRBALOX15THRA
2-Ethoxyethanol SCHEMBL9321382 0.85 ALDH1A1 (0.64) TSHRALDH1A1THRBALOX15HTT
Ether SCHEMBL28161425 0.83 TSHR (0.50) TSHRALDH1A1ALOX15
Dimethylformamide SCHEMBL8357843 0.83 ALDH1A1 (0.73) TSHRALDH1A1THRBALOX15THRA
Ether SCHEMBL8913501 0.81 TSHR (0.47) TSHRALDH1A1ALOX15
Ether SCHEMBL18985182 0.79 TSHR (0.45) TSHRALDH1A1ALOX15
SCHEMBL23085322 0.79 ALOX15 (0.38) TSHRALDH1A1THRBALOX15THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104968662-B Azole benzene derivative 帝人制药株式会社 2018-03-30 — — CN disclosed