Ether

Ether

SCHEMBL335388

CCOCC.CN(C)C=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 1/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL4609718 1.00 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ALOX15
Ether SCHEMBL28161425 0.94 TSHR (0.50) TSHRALDH1A1ALOX15CYP2C9
Ether SCHEMBL8913501 0.92 TSHR (0.47) TSHRALDH1A1ALOX15CYP2C9
Ether SCHEMBL18985182 0.89 TSHR (0.45) TSHRALDH1A1ALOX15CYP2C9
Dimethylformamide SCHEMBL28207129 0.88 TSHR (0.50) TSHRALDH1A1ALOX15
Ether SCHEMBL28347512 0.87 TSHR (0.43) TSHRALDH1A1CYP2C9
Ether SCHEMBL27748257 0.87 TSHR (0.43) TSHR
Dimethylformamide SCHEMBL10802383 0.86 TSHR (0.47) TSHRALDH1A1ALOX15
Ether SCHEMBL8895247 0.83 TSHR (0.39) TSHR
Tetrahydrofuran SCHEMBL10573397 0.82 TSHR (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107954822-A A kind of method for preparing diaryl acetylene compound 浙江大学 2018-04-24 CN claimed
EP-1688410-B1 CRYSTAL OF PHENYLALANINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME AJINOMOTO KK (JP) 2014-03-05 EP claimed
EP-1688410-A1 CRYSTAL OF PHENYLALANINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Ajinomoto Co., Inc. (JP) 2006-08-09 EP claimed
EP-0478874-A2 Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them AMERICAN CYANAMID COMPANY (US) 1992-04-08 EP claimed
EP-0046658-B1 PRODUCTION OF TRIAZOLYLVINYL KETONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-10-24 EP claimed
EP-0005524-A1 Omega-(1,3-dithiolan-2-imino)substituted acetic acids, process for their preparation and pharmaceutical compositions containing them MERRELL DOW PHARMACEUTICALS, INC. (US) 1979-11-28 EP claimed
WO-2023133876-A1 FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF 嘉庚创新实验室 2023-07-20 WO disclosed
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-03-10 US disclosed
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-07-29 US disclosed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP disclosed
CN-110431520-A Conductive film, touch panel and image display device DAINIPPON PRINTING CO LTD 2019-11-08 CN disclosed
CN-110337475-A Membrane with hydrophobically modified cellulose fibers and oil 花王株式会社 2019-10-15 CN disclosed
CN-109275335-B The manufacturing method of composition and composition 住友化学株式会社 2019-10-15 CN disclosed
US-4271068-A Process for the manufacture of cystine-containing peptides CIBA-GEIGY CORPORATION (US) 1981-06-02 US disclosed
US-4260774-A IMMUNOSUPPRESSANTS, ANTITUMOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-04-07 US disclosed
US-4172892-A Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid CARLO ERBA S.P.A. (IT) 1979-10-30 US disclosed
US-4159981-A CYCLIC POLYPEPTIDES, DEETHERIFICATION, DEESTERIFICATION CIBA-GEIGY CORPORATION (US) 1979-07-03 US disclosed
US-4154830-A ANTIBIOTICS, BACTERICIDES FOR INFECTIONS CARLO ERBA S.P.A. (IT) 1979-05-15 US disclosed
US-4103089-A ANTIHISTAMINES MERRELL TORAUDE ET COMPAGNIE (FR) 1978-07-25 US disclosed
US-3934008-A PEPTIDES, HYPOCALCAEMIC CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN TSHR 1863/4885ALDH1A1 2263/4885MAPK1 3530/4885
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN TSHR 1863/4885ALDH1A1 2263/4885MAPK1 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.