SCHEMBL28207459

SCHEMBL28207459

O=C(Cc1ccc(OCc2ccccc2)cc1)OCc1ccccc1.O=C(Cc1ccc(OCc2ccccc2)cc1)OCc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.77
MAPK1 P28482 1/20 0.77
L3MBTL1 Q9Y468 1/20 0.77
PRKCA P17252 1/20 0.64
PRKCD Q05655 1/20 0.64
ALOX5 P09917 5/20 0.63
NR4A1 P22736 1/20 0.60
NR4A2 P43354 1/20 0.60
NR4A3 Q92570 1/20 0.60
FFAR1 O14842 1/20 0.59
FFAR4 Q5NUL3 1/20 0.59
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC6A2 P23975 1/20 0.58
CYP2C19 P33261 1/20 0.58
PTGS2 P35354 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HIF1A Q16665 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2658123 1.00 ALDH1A1 (0.77) ALDH1A1MAPK1L3MBTL1PRKCAPRKCD
SCHEMBL20867886 1.00 ALDH1A1 (0.77) ALDH1A1MAPK1L3MBTL1PRKCAPRKCD
SCHEMBL6784181 0.89 ALDH1A1 (0.96) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL7326238 0.89 ALDH1A1 (0.70) ALDH1A1MAPK1L3MBTL1PRKCAPRKCD
SCHEMBL1203178 0.89 ALOX5 (0.67) ALDH1A1MAPK1L3MBTL1PRKCAPRKCD
SCHEMBL7801266 0.88 NR4A1 (0.62) ALDH1A1MAPK1L3MBTL1ALOX5NR4A1
SCHEMBL361779 0.88 ALDH1A1 (1.00) ALDH1A1MAPK1L3MBTL1LMNASLC6A2
SCHEMBL2669742 0.86 L3MBTL1 (0.66) ALDH1A1MAPK1L3MBTL1PRKCAPRKCD
SCHEMBL10824903 0.85 NPC1 (0.62) ALDH1A1MAPK1L3MBTL1FFAR1MAOB
SCHEMBL1171464 0.85 ALDH1A1 (0.74) ALDH1A1MAPK1L3MBTL1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107880085-A One kind utilizes [Rmim] [OSO2OR] Lewis acid ions liquid system synthesis rhodioside method 枣庄学院 2018-04-06 CN disclosed