Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | PLD2 | O14939 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206987 | 0.89 | KIF11 (0.47) | KIF11RAB9ASMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL28062889 | 0.85 | RAB9A (0.38) | KIF11RAB9ASMN1; SMN2PARP1KDM4E | |
| SCHEMBL28024559 | 0.85 | RAB9A (0.52) | KIF11RAB9APARP1KDM4ECSNK2A1 | |
| SCHEMBL28207450 | 0.80 | RAB9A (0.52) | KIF11RAB9ASMN1; SMN2PARP1KDM4E | |
| SCHEMBL28207427 | 0.79 | KDM4E (0.50) | PARP1KDM4E | |
| SCHEMBL28207445 | 0.79 | GPR17 (0.48) | SMN1; SMN2KDM4EDYRK1A | |
| SCHEMBL28207448 | 0.76 | KIF11 (0.51) | KIF11KDM4EFGFR1KDR | |
| SCHEMBL28062758 | 0.76 | HSD17B10 (0.43) | RAB9ASMN1; SMN2KDM4EDYRK1A | |
| SCHEMBL26250360 | 0.75 | KDM4E (0.57) | KIF11RAB9AKDM4E | |
| SCHEMBL28207452 | 0.75 | KIF11 (0.50) | KIF11PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892485-B | 2 perfluoroalkyl indole derivativeses and its synthetic method | 上海麦克林生化科技有限公司 | 2018-03-23 | — | — | CN | disclosed |