Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062838 | 0.90 | KDM4E (0.40) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL28207487 | 0.85 | KIF11 (0.43) | RAB9ASMN1; SMN2KDM4EFGFR1FLT1 | |
| SCHEMBL28062758 | 0.78 | HSD17B10 (0.43) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL28207450 | 0.76 | RAB9A (0.52) | RAB9ASMN1; SMN2KDM4EALDH1A1FGFR1 | |
| SCHEMBL28207427 | 0.76 | KDM4E (0.50) | ALOX15KDM4EHPGDPARP1 | |
| SCHEMBL28207445 | 0.76 | GPR17 (0.48) | ALOX15SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL28206987 | 0.74 | KIF11 (0.47) | RAB9ASMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL28207448 | 0.73 | KIF11 (0.51) | KDM4EGAAFGFR1KDRKIF11 | |
| SCHEMBL28062757 | 0.73 | ALDH1A1 (0.42) | RAB9ASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL26250360 | 0.72 | KDM4E (0.57) | RAB9AKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |