Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591645 | 0.88 | CA1 (0.48) | KMT2ARAB9AMAPTMAPK1MAOB | |
| SCHEMBL28904555 | 0.81 | APP (0.41) | KMT2ARAB9AMAPTMAPK1NPC1 | |
| SCHEMBL1420029 | 0.81 | ESR2 (0.59) | MEN1KMT2ARAB9AMAPTMAPK1 | |
| SCHEMBL6417992 | 0.81 | CA4 (0.44) | MEN1KMT2ARAB9ANPSR1MAPT | |
| SCHEMBL28150942 | 0.79 | ESR2 (0.48) | RAB9AMAPTMAPK1MAOBNPC1 | |
| SCHEMBL177569 | 0.75 | MEN1 (0.59) | MEN1KMT2ARAB9ANPSR1MAPT | |
| SCHEMBL28157776 | 0.75 | APP (0.55) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL7123909 | 0.74 | HPGD (0.42) | RAB9AMAOBNPC1HPGDALDH1A1 | |
| SCHEMBL4468568 | 0.73 | MEN1 (0.40) | MEN1KMT2ARAB9ANPSR1MAPT | |
| SCHEMBL1420156 | 0.73 | MAOB (0.50) | MEN1KMT2ARAB9ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348060-B | A kind of preparation method of 1,2 derovatives | 江苏强盛功能化学股份有限公司 | 2018-03-27 | — | — | CN | disclosed |