SCHEMBL177569

SCHEMBL177569

COc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
RAB9A P51151 3/20 0.59
MAPK1 P28482 3/20 0.59
MAPT P10636 2/20 0.59
RXFP1 Q9HBX9 2/20 0.59
LMNA P02545 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
ESR2 Q92731 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
MAOB P27338 2/20 0.53
MAOA P21397 1/20 0.53
NPC1 O15118 2/20 0.52
TP53 P04637 1/20 0.52
CASP3 P42574 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10047628 0.93 LTA4H (0.54) MEN1KMT2ARAB9AMAPK1MAPT
SCHEMBL15679887 0.93 ABL1 (0.59) MEN1KMT2ARAB9AMAPK1MAPT
SCHEMBL9301 0.92
SCHEMBL3862399 0.91 ALDH1A1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
SCHEMBL10605468 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
Bromomethane SCHEMBL9702151 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
Phosphine SCHEMBL9754815 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
SCHEMBL5466009 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
Magnesium SCHEMBL31191739 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT
SCHEMBL109479 0.89 CA1 (0.65) MEN1KMT2ARAB9AMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025066980-A1 PHOSPHORUS-CONTAINING TRIANHYDRIDE MONOMER AND PREPARATION METHOD THEREFOR, AND POLYIMIDE MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 比亚迪股份有限公司 2025-04-03 WO claimed
CN-118221734-A Phosphoric dianhydride monomer and preparation method thereof, polyimide material and preparation method and application thereof 比亚迪股份有限公司 2024-06-21 CN claimed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
WO-2025108154-A1 POLYCYCLIC COMPOUND AND USE THEREOF HUAHUI HEALTH LTD. (CN) 2025-05-30 WO disclosed
CN-119781244-A Photosensitive composition for color filter, image display device, and solid-state imaging element 爱天思株式会社 2025-04-08 CN disclosed
CN-119751504-A Acid compound, polyimide covalent organic framework, and preparation methods and applications thereof 比亚迪股份有限公司 2025-04-04 CN disclosed
WO-2025066980-A1 PHOSPHORUS-CONTAINING TRIANHYDRIDE MONOMER AND PREPARATION METHOD THEREFOR, AND POLYIMIDE MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 比亚迪股份有限公司 2025-04-03 WO disclosed
CN-119504463-A Hole transport material, synthesis method, perovskite solar cell and preparation method 晶澳(扬州)太阳能科技有限公司 2025-02-25 CN disclosed
US-12115154-B2 Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) SRX CARDIO, LLC (US) 2024-10-15 US disclosed
CN-118324596-A Synthesis method of biaryl compound 新疆大学 2024-07-12 CN disclosed
CN-118221734-A Phosphoric dianhydride monomer and preparation method thereof, polyimide material and preparation method and application thereof 比亚迪股份有限公司 2024-06-21 CN disclosed
WO-1998003166-A1 THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS MONSANTO COMPANY (US) 1998-01-29 WO disclosed
EP-0343606-B1 An engineering plastic composition and an article made of the same SEIKISUI CHEMICAL CO LTD (JP) 1995-01-18 EP disclosed
EP-0438754-B1 Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition DAINIPPON INK & CHEMICALS (JP) 1994-08-17 EP disclosed
EP-0390945-B1 Process for preparing 4,4'''-dihydroxyquater-phenyl or derivatives thereof SANKO KAIHATSU KAGAKU KENK (JP) 1993-11-18 EP disclosed
US-5064564-A Ferroelectric liquid crystal display DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-11-12 US disclosed
EP-0438754-A1 Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-07-31 EP disclosed
US-5011879-A With adjuvants of p-quaterphenyl or its hydroxy, alkoxy or alkyl ester derivatives; melt viscosity, heat resistance, molding materials SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-30 US disclosed
EP-0390945-A1 Process for preparing 4,4'''-dihydroxyquater-phenyl or derivatives thereof Sanko Kaihatsu Kagaku Kenkyusho (JP) 1990-10-10 EP disclosed
EP-0343606-A1 An engineering plastic composition and an article made of the same SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12115154-B2 Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) PCSK9, PCSK6, PCSK7 MEN1 1661/4885KMT2A 3880/4885RAB9A 753/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 MEN1 3186/4885KMT2A 2541/4885RAB9A 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.