Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 3/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PPIG | Q13427 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278947 | 0.84 | PPID (0.42) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| SCHEMBL30505642 | 0.84 | PPID (0.42) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27767646 | 0.83 | PPID (0.41) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5710126 | 0.83 | PPID (0.41) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| SCHEMBL28207903 | 0.80 | CA1 (0.36) | — | |
| SCHEMBL16063626 | 0.78 | HTT (0.48) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| SCHEMBL4003642 | 0.77 | HTT (0.55) | PPIDL3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL11553376 | 0.74 | LTA4H (0.34) | PPIDPPIBPPIAPPIGKMT2A | |
| SCHEMBL7307996 | 0.72 | PPID (0.44) | PPIDPPIBPPIAPPIGL3MBTL1 | |
| SCHEMBL11548859 | 0.72 | ALDH1A1 (0.40) | L3MBTL1KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903269-B | Preparation method of anagrelide trichloro derivative | 湖北省宏源药业科技股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-107903269-B | Preparation method of anagrelide trichloro derivative | 湖北省宏源药业科技股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-107903269-B | Preparation method of anagrelide trichloro derivative | 湖北省宏源药业科技股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-107903269-A | A kind of preparation method of three chlorine derivative of anagrelide | 湖北省宏源药业科技股份有限公司 | 2018-04-13 | — | — | CN | disclosed |