Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030898 | 0.77 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL1013096 | 0.76 | CYP2C19 (0.44) | HRH3TMEM97CARM1PRMT6SIGMAR1 | |
| SCHEMBL7530803 | 0.75 | ESR1 (0.40) | CTSLCTSBCTSKFFAR1 | |
| SCHEMBL21460359 | 0.75 | SMN1; SMN2 (0.47) | CYP2C19TACR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11508468 | 0.75 | FFAR1 (0.44) | HRH3SMN1; SMN2FFAR1SLC6A2SLC6A4 | |
| SCHEMBL16047458 | 0.73 | KMT2A (0.39) | SMN1; SMN2FFAR1 | |
| SCHEMBL1578423 | 0.72 | SPHK2 (0.52) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12371297 | 0.72 | FFAR1 (0.51) | FFAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4070124 | 0.71 | SLC18A3 (0.40) | HRH3 | |
| Oxalic Acid SCHEMBL5783002 | 0.71 | HRH3 (0.43) | HRH3SIGMAR1CYP2C19SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107880046-B | A kind of preparation method of dibenzo [b, e] azepines compound | 青岛农业大学 | 2019-11-15 | — | — | CN | disclosed |
| CN-107880046-A | A kind of preparation method of dibenzo [b, e] azepines compound | 青岛农业大学 | 2018-04-06 | — | — | CN | disclosed |