Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508468 | 0.77 | FFAR1 (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL4070124 | 0.74 | SLC18A3 (0.40) | KMT2ACHRNB4CHRNA3CHRNB2CHRNA7 | |
| SCHEMBL11498525 | 0.72 | FFAR1 (0.40) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL15515642 | 0.72 | KMT2A (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL11030898 | 0.70 | FFAR1 (0.38) | FFAR1CHRNA7MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL30228507 | 0.70 | MBTD1 (0.37) | KMT2AFFAR1MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL23064524 | 0.68 | KMT2A (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL484011 | 0.68 | KMT2A (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL8502504 | 0.68 | L3MBTL1 (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL8526124 | 0.68 | KMT2A (0.44) | KMT2AFFAR1CHRNB4CHRNA3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-111333626-B | Phenyl pyrrolidine compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-111333625-B | Phenyl pyrrolidine compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-111333637-B | Phenyl pyrrolidine derivative and preparation method thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20220056014-A1 | PHENYLPYRROLIDINE COMPOUND AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2022-02-24 | — | — | US | disclosed |
| EP-3901146-A1 | PHENYLPYRROLIDINE COMPOUND AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-10781202-B2 | Azetidinyloxyphenylpyrrolidine compounds | ELI LILLY AND COMPANY (US) | 2020-09-22 | — | — | US | disclosed |
| US-10781202-B2 | Azetidinyloxyphenylpyrrolidine compounds | ELI LILLY AND COMPANY (US) | 2020-09-22 | — | — | US | disclosed |
| US-9034864-B2 | Azetidinyloxyphenylpyrrolidine compounds | ELI LILLY AND COMPANY (US) | 2015-05-19 | — | — | US | disclosed |
| US-9034864-B2 | Azetidinyloxyphenylpyrrolidine compounds | ELI LILLY AND COMPANY (US) | 2015-05-19 | — | — | US | disclosed |
| US-20150133423-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | LILLY CO ELI (US) | 2015-05-14 | — | — | US | disclosed |
| US-20150133423-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | LILLY CO ELI (US) | 2015-05-14 | — | — | US | disclosed |
| WO-2014159012-A9 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014159012-A9 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014159012-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014159012-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140275002-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275002-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781202-B2 | Azetidinyloxyphenylpyrrolidine compounds | QDPR, TACR1, PDE3B | KMT2A 3122/4885FFAR1 2373/4885CHRNB4 290/4885 |
| US-20150133423-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | QDPR, AZI2, TACR1 | KMT2A 1266/4885FFAR1 2177/4885CHRNB4 439/4885 |
| US-20220056014-A1 | PHENYLPYRROLIDINE COMPOUND AND USE THEREOF | PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AVPR2 | KMT2A 3188/4885FFAR1 645/4885CHRNB4 1814/4885 |
| US-20140275002-A1 | AZETIDINYLOXYPHENYLPYRROLIDINE COMPOUNDS | QDPR, AZI2, TACR1 | KMT2A 1266/4885FFAR1 2177/4885CHRNB4 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.