Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18340789 | 1.00 | L3MBTL1 (0.46) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL18272975 | 0.93 | LMNA (0.50) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL19401688 | 0.93 | LMNA (0.50) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL28631898 | 0.93 | LMNA (0.50) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| Trifluoroacetic Acid SCHEMBL20263694 | 0.89 | SLC1A3 (0.51) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| Hydrochloric Acid SCHEMBL29687309 | 0.88 | LMNA (0.46) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 | |
| Trifluoroacetic Acid SCHEMBL3046988 | 0.84 | ALPI (0.46) | SLC1A3SLC1A1ANPEP | |
| Trifluoroacetic Acid SCHEMBL4082678 | 0.83 | CTSS (0.49) | ATMCTSSCTSLCTSKCTSB | |
| Trifluoroacetic Acid SCHEMBL6533136 | 0.82 | SLC1A1 (0.41) | SMN1; SMN2SLC1A3SLC1A1ATMCTSS | |
| Trifluoroacetic Acid SCHEMBL28688130 | 0.81 | CTSS (0.53) | L3MBTL1LMNASMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107921288-A | The targeting conjugate of KSP inhibitor | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |