Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL28603345 | 1.00 | SLC7A5 (0.52) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL2205278 | 1.00 | SLC7A5 (0.52) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL3492177 | 0.94 | SLC7A5 (0.46) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL18339169 | 0.92 | SLC7A5 (0.44) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL9282617 | 0.92 | SLC7A5 (0.44) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL9282615 | 0.92 | SLC7A5 (0.44) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL28368606 | 0.92 | SLC7A5 (0.44) | SLC7A5ITGA4ANPEPRNPEPDNPEP | |
| Tyrosine SCHEMBL6665573 | 0.92 | SLC7A5 (0.56) | SLC7A5ITGA4ITGB1ALPIPKM | |
| Tyrosine SCHEMBL4352800 | 0.92 | SLC7A5 (0.61) | SLC7A5ITGA4ITGB1ALPIPKM | |
| Tyrosine SCHEMBL4205059 | 0.92 | SLC7A5 (0.61) | SLC7A5ITGA4ITGB1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873944-A | A kind of industrialized production rapeseed active peptide and preparation method | 林峰 | 2018-04-06 | — | — | CN | disclosed |