SCHEMBL28210380

SCHEMBL28210380

CCCC(COC)C([O])=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.46
HDAC2 Q92769 3/20 0.46
CHRM1 P11229 2/20 0.46
CHRM3 P20309 2/20 0.46
ADRA1A P35348 2/20 0.46
AKR1A1 P14550 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
HRH1 P35367 1/20 0.46
DRD3 P35462 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
NFKB1 P19838 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HDAC7 Q8WUI4 3/20 0.41
HDAC8 Q9BY41 3/20 0.41
HDAC6 Q9UBN7 3/20 0.41
HDAC9 Q9UKV0 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141328 0.82 HDAC1 (0.65) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL28210977 0.81
SCHEMBL28244713 0.80 CA1 (0.53) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL515242 0.80 HDAC1 (0.60) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL27494786 0.78 HDAC1 (0.47) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL275821 0.75
SCHEMBL19409190 0.75 HDAC1 (0.40) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL28210984 0.73 CA2 (0.41) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL8811133 0.71 CA2 (0.54) HDAC1HDAC2CHRM1CHRM3ADRA1A
SCHEMBL7200252 0.71 CA2 (0.53) TDP1CYP3A4TSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107892729-A The copolymer and manufacture method of (methyl) acrylic acid triisopropylsilyl ester and (methyl) acrylic acid derivative 信越化学工业株式会社 2018-04-10 CN disclosed