Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604558 | 0.81 | GPR84 (0.73) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL4220443 | 0.79 | GPR84 (0.69) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL31415113 | 0.79 | GPR84 (0.74) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL11273551 | 0.79 | GPR84 (0.69) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL13715344 | 0.79 | GPR84 (0.69) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL2533008 | 0.79 | GPR84 (0.69) | GPR84SLC6A4FFAR1HTR2AHTR2C | |
| SCHEMBL28273847 | 0.78 | GPR17 (0.58) | GPR84SLC6A4HTR2AMAPT | |
| SCHEMBL20898137 | 0.78 | HTR2C (0.65) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1225093 | 0.77 | SLC6A4 (0.68) | GPR84SLC6A4FFAR1NR4A2HTR2A | |
| SCHEMBL19604580 | 0.77 | GPR84 (0.67) | GPR84SLC6A4FFAR1NR4A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037239-B | A kind of preparation method of the acetic acid of 4 chloro-indole 3 | 苏州卡耐博生物技术有限公司 | 2018-04-06 | — | — | CN | disclosed |