Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 10/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655761 | 0.86 | HPGDS (0.45) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL27369174 | 0.85 | HPGDS (0.47) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL8911377 | 0.85 | HDAC1 (0.55) | HRH1HPGDSKDM4ESMN1; SMN2HDAC1 | |
| SCHEMBL2821094 | 0.84 | CYP2D6 (0.49) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL11396105 | 0.81 | HPGDS (0.48) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23146081 | 0.77 | CYP2A6 (0.61) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL152405 | 0.77 | HPGDS (0.50) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL2226543 | 0.77 | HDAC1 (0.52) | CYP2A6HPGDSKDM4ESMN1; SMN2HDAC1 | |
| SCHEMBL8086775 | 0.73 | KDM4E (0.57) | CYP2A6CYP2E1CYP2C9CYP2B6CYP3A4 | |
| SCHEMBL16601901 | 0.72 | KDM4E (0.59) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229082-A | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 1999-09-22 | — | — | CN | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | claimed |
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | disclosed |