Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 4/20 | 0.51 |
| ▸ | IL6 | P05231 | 3/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAX | P61244 | 1/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278806 | 0.81 | IKBKB (0.47) | RAB9A | |
| SCHEMBL28278807 | 0.81 | IKBKB (0.47) | RAB9A | |
| SCHEMBL28211015 | 0.78 | TNF (0.51) | TNFIL6MYCMAXCYP24A1 | |
| SCHEMBL28377055 | 0.78 | HSD11B1 (0.50) | RAB9ACCR3 | |
| SCHEMBL28377057 | 0.78 | HSD11B1 (0.50) | RAB9ACCR3 | |
| SCHEMBL28765345 | 0.78 | DYRK2 (0.47) | PIM1 | |
| SCHEMBL28572914 | 0.74 | ALDH1A1 (0.47) | PIM1 | |
| SCHEMBL9523178 | 0.74 | GSK3B (0.48) | — | |
| SCHEMBL28154611 | 0.74 | CYP1A2 (0.49) | PIM1PIM2 | |
| SCHEMBL28154612 | 0.74 | CYP1A2 (0.49) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037252-B | N- substitutions -3,5- two (2- (trifluoromethyl) benzal) piperidin-4-one-derivative and preparation method and application | 温州医科大学 | 2018-05-04 | — | — | CN | disclosed |