Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458311 | 0.85 | MAPT (0.48) | ERN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL18458067 | 0.84 | CASP6 (0.55) | ERN1LMNAEIF4EHCAR3TSHR | |
| SCHEMBL13011479 | 0.82 | VCAM1 (0.52) | ERN1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL11541099 | 0.81 | MAPT (0.53) | ALDH1A1LMNAMAPK1HTTKMT2A | |
| SCHEMBL28211105 | 0.79 | MAPT (0.44) | ALDH1A1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL18458068 | 0.76 | POLB (0.56) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL28858691 | 0.75 | ERN1 (0.38) | ERN1ALDH1A1KMT2ASMN1; SMN2EIF4E | |
| SCHEMBL28211111 | 0.74 | ERN1 (0.41) | ERN1ALDH1A1SMN1; SMN2EIF4EMAOA | |
| SCHEMBL28211113 | 0.74 | HTT (0.54) | ERN1ALDH1A1LMNAMAPK1HTT | |
| SCHEMBL5913395 | 0.74 | ERN1 (0.40) | ERN1ALDH1A1KMT2ASMN1; SMN2EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922375-A | Target the antitumoral compounds and its application method of IDH2 mutation | 正大天晴药业集团股份有限公司 | 2018-04-17 | — | — | CN | disclosed |