Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211329 | 1.00 | FKBP1A (0.50) | FKBP1AKCNT1ALDH1A1HPGDSLC6A9 | |
| SCHEMBL28211323 | 0.79 | FKBP1A (0.61) | FKBP1AKCNT1ALDH1A1HPGDLMNA | |
| SCHEMBL28211330 | 0.71 | FKBP1A (0.57) | FKBP1AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28211332 | 0.71 | FKBP1A (0.57) | FKBP1AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28215702 | 0.67 | TSHR (0.45) | FKBP1AKCNT1ALDH1A1KMT2ATSHR | |
| SCHEMBL15257320 | 0.66 | TSHR (0.52) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| SCHEMBL15139607 | 0.66 | POLB (0.71) | FKBP1AALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL28211313 | 0.66 | FKBP1A (0.71) | FKBP1AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18425541 | 0.64 | FKBP1A (0.44) | FKBP1AALDH1A1LMNAKMT2AUSP2 | |
| SCHEMBL18425539 | 0.64 | FKBP1A (0.44) | FKBP1AALDH1A1LMNAKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980040-A | 1,3,4- oxadiazoles sulfamide derivative as 6 inhibitor of histone deacetylase enzyme and the medical composition containing it | 株式会社钟根堂 | 2018-05-01 | — | — | CN | disclosed |