Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.61 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211337 | 0.79 | FKBP1A (0.50) | FKBP1AKCNT1TSHRALDH1A1HPGD | |
| SCHEMBL28211329 | 0.79 | FKBP1A (0.50) | FKBP1AKCNT1TSHRALDH1A1HPGD | |
| SCHEMBL28215702 | 0.78 | TSHR (0.45) | FKBP1AKCNT1TSHRALDH1A1KMT2A | |
| SCHEMBL28858447 | 0.78 | CHRNB4 (0.45) | ALDH1A1POLB | |
| SCHEMBL28211341 | 0.78 | KCNT1 (0.53) | FKBP1AKCNT1TSHRALDH1A1KMT2A | |
| SCHEMBL15139607 | 0.74 | POLB (0.71) | FKBP1AALDH1A1KMT2AGLAMEN1 | |
| SCHEMBL28211313 | 0.74 | FKBP1A (0.71) | FKBP1AALDH1A1HPGDKMT2AGLA | |
| SCHEMBL25734171 | 0.73 | ATM (0.58) | FKBP1ATSHRALDH1A1HPGDKMT2A | |
| SCHEMBL28144325 | 0.71 | ADRB2 (0.55) | CA1CA2CA7LMNA | |
| SCHEMBL28216337 | 0.70 | HPGD (0.51) | ALDH1A1HPGDKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980040-A | 1,3,4- oxadiazoles sulfamide derivative as 6 inhibitor of histone deacetylase enzyme and the medical composition containing it | 株式会社钟根堂 | 2018-05-01 | — | — | CN | disclosed |