Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392069 | 0.83 | MAPT (0.58) | FKBP1AKMT2AGLAPOLBCA1 | |
| SCHEMBL4710815 | 0.83 | HTR6 (0.51) | FKBP1AKMT2AGLAPOLBCA1 | |
| SCHEMBL28211330 | 0.80 | FKBP1A (0.57) | FKBP1AALDH1A1KMT2AGLAHSD17B10 | |
| SCHEMBL28211332 | 0.80 | FKBP1A (0.57) | FKBP1AALDH1A1KMT2AGLAHSD17B10 | |
| SCHEMBL15139607 | 0.80 | POLB (0.71) | FKBP1AALDH1A1KMT2AGLAHSD17B10 | |
| SCHEMBL18007745 | 0.74 | FKBP1A (0.62) | FKBP1AALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL28210750 | 0.74 | FKBP1A (0.49) | FKBP1AALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL28211323 | 0.74 | FKBP1A (0.61) | FKBP1AALDH1A1KMT2AGLAHSD17B10 | |
| SCHEMBL28211311 | 0.74 | FKBP1A (0.42) | FKBP1AALDH1A1KMT2AGLAHPGD | |
| SCHEMBL5955341 | 0.74 | MAPT (0.69) | ALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980040-A | 1,3,4- oxadiazoles sulfamide derivative as 6 inhibitor of histone deacetylase enzyme and the medical composition containing it | 株式会社钟根堂 | 2018-05-01 | — | — | CN | disclosed |