Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | NGFR | P08138 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211430 | 0.84 | NTRK1 (0.54) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL19086870 | 0.83 | NPC1 (0.53) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL28825720 | 0.82 | NTRK1 (0.53) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL17578567 | 0.80 | HIF1A (0.67) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4727925 | 0.78 | NPY5R (0.65) | NTRK1NGFRMAPTNPC1RAB9A | |
| SCHEMBL7975873 | 0.74 | MAPT (0.52) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL28211432 | 0.73 | ALDH1A1 (0.61) | MAPTPOLBNPC1RAB9AKMT2A | |
| SCHEMBL19113738 | 0.73 | HIF1A (0.52) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL2727308 | 0.72 | NTRK1 (1.00) | NTRK1NGFRMAPTPOLBNPC1 | |
| SCHEMBL7873648 | 0.71 | NTRK1 (0.53) | NTRK1NGFRMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384687-B | Quinolinones compound and its applied in medicine | 广东东阳光药业有限公司 | 2018-05-01 | — | — | CN | disclosed |