SCHEMBL28211609

SCHEMBL28211609

O=S(=O)(Oc1cc(F)cc2ccccc12)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HPGD P15428 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP2A6 P11509 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31722992 0.87 ADORA2A (0.39) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL5088679 0.86 DRD2 (0.36) CYP1A2PDE4APDE4CPDE4DCYP2A6
SCHEMBL6937631 0.85 GPR84 (0.45) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL19959255 0.84 CYP1A2 (0.43) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL15998741 0.84 HTT (0.39) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL2656359 0.84 NQO2 (0.43) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL30064989 0.84 NQO2 (0.43) ADORA2AADORA1KDM4EALDH1A1HSD17B10
SCHEMBL17945537 0.82 KMT2A (0.40) KDM4EALDH1A1HSD17B10CYP1A2MEN1
SCHEMBL1408383 0.82 TUBB4A (0.45) KDM4EALDH1A1CYP1A2HPGDCYP2A6
SCHEMBL16540074 0.82 NPC1 (0.34) ADORA2AADORA1ALDH1A1CYP1A2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107892702-A Organic electroluminescent material and device 环球展览公司 2018-04-10 CN disclosed