Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL416962 | 0.98 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Alcohol SCHEMBL21924395 | 0.98 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Alcohol SCHEMBL28115493 | 0.98 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Alcohol SCHEMBL27785914 | 0.98 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Propane SCHEMBL3563886 | 0.93 | GAA (0.54) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Propane SCHEMBL28408609 | 0.93 | GAA (0.54) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Propanol SCHEMBL28768546 | 0.91 | ALDH1A1 (0.49) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Ethylene Glycol SCHEMBL6046494 | 0.91 | GAA (0.52) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Ethylene Glycol SCHEMBL1936216 | 0.91 | GAA (0.52) | GAAALDH1A1SMN1; SMN2LMNAKDM4E | |
| Ethylene Glycol SCHEMBL1247518 | 0.91 | GAA (0.52) | GAAALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149552-B | Preparation method of high-wear-resistance melamine finishing resin | 安徽弘源化工科技有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-114315627-B | Method for synthesizing doxycycline dehydrate by catalyzing with normal-temperature ionic liquid and zeolite | 扬州联博药业有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-112390658-B | Mechanical processing and forming method for oxide foamed ceramic material | 中国工程物理研究院激光聚变研究中心 | 2022-05-31 | — | — | CN | claimed |
| CN-114315627-A | Method for synthesizing doxycycline dehydrate by catalyzing with normal-temperature ionic liquid and zeolite | 扬州联博药业有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114149552-A | Preparation method of high-wear-resistance melamine finishing resin | 安徽弘源化工科技有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-112390658-A | Mechanical processing and forming method for oxide foamed ceramic material | 中国工程物理研究院激光聚变研究中心 | 2021-02-23 | — | — | CN | claimed |
| CN-109232909-B | Method for separating high-activity lignin from agriculture and forestry biomass | 盐城工学院 | 2020-12-01 | — | — | CN | claimed |
| CN-109796400-A | A kind of toluenesulfonic acid Sorafenib crystal form and preparation method thereof | 四川科伦药物研究院有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-107474659-A | A kind of high-strength abrasion-proof water paint | 芜湖县双宝建材有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-107353778-A | A kind of easily attachment cracking resistance aqueous epoxide resin paint | 芜湖县双宝建材有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-106449147-A | CMS/MnO2/PPY (carbon microsphere/manganese dioxide/polypyrrole) composite electrode material, as well as preparation method and application thereof | 广州大学 | 2017-02-22 | — | — | CN | claimed |
| CN-114989103-B | Preparation method of 2-methoxy-3- (1-methyl-1H-1, 2, 4-triazole-3-yl) aniline | 杭州科巢生物科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118221699-A | Pharmaceutically acceptable salts and crystal forms of KRAS G12D inhibitor and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2024109871-A1 | PHARMACEUTICALLY ACCEPTABLE SALT OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, CRYSTAL FORM THEREOF, AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| WO-2024109727-A1 | CRYSTALLINE FORM OF PHARMACEUTICALLY ACCEPTABLE SALT OF PYRAZOLO HETEROARYL DERIVATIVE | 江苏恒瑞医药股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-1090279-A | Be used for the treatment of HIV and other retroviral pyran-2-ones and 5,6-dihydropyrane-2-ketone | UPJOHN CO (US) | 1994-08-03 | — | — | CN | disclosed |
| WO-1993012076-A1 | REAGENTS FOR AUTOMATED SYNTHESIS OF PEPTIDE ANALOGS | CORVAS INTERNATIONAL INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| CN-1068119-A | Octadecyl-[2-(N-methyl piperidine subbase)-ethyl]-phosphoric acid ester and preparation method thereof | ATSA MEDICA AG (DE) | 1993-01-20 | — | — | CN | disclosed |
| EP-0020058-B1 | TOTAL SYNTHESIS OF (1RS, 4SR, 5RS)-4-(4,8-DIMETHYL-5-HYDROXY-7-NONENYL)-4-METHYL-3,8-DIOXABICYCLO (3.2.1) OCTANE-1-ACETIC ACID, AND INTERMEDIATES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4237054-A | Total synthesis of (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1] octane-1-acetic acid | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |