Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | FYN | P06241 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.49 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.49 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042378 | 0.86 | MAPT (0.43) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL17626004 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ATP53STAT1 | |
| SCHEMBL3947270 | 0.81 | PLK1 (0.40) | SMN1; SMN2TP53MAPTALDH1A1KDM4E | |
| SCHEMBL17626272 | 0.78 | HTT (0.60) | SMN1; SMN2NPC1RAB9AFYNTP53 | |
| SCHEMBL17626288 | 0.76 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3943459 | 0.75 | BRAF (0.33) | SMN1; SMN2MAPTALDH1A1BRAFMEN1 | |
| SCHEMBL3948719 | 0.75 | GRIA2 (0.37) | SMN1; SMN2FYNMAPTALDH1A1KDM4E | |
| SCHEMBL1764786 | 0.75 | MAPT (0.70) | SMN1; SMN2NPC1RAB9ATP53STAT1 | |
| SCHEMBL3140270 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AFYNTP53 | |
| SCHEMBL28527743 | 0.75 | MAPT (0.76) | SMN1; SMN2NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849013-A | It is used for the cyanopyrrole alkanes for the treatment of cancer as DUB inhibitor | 特殊治疗有限公司 | 2018-03-27 | — | — | CN | disclosed |