Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291948 | 0.85 | MMP8 (0.56) | MMP8CNR2TSHRKEAP1ANPEP | |
| SCHEMBL7751974 | 0.84 | TSHR (0.47) | MMP8CNR2TSHRPPARGPPARA | |
| SCHEMBL27514855 | 0.82 | GRIK1 (0.53) | MMP8KEAP1PPARGPPARASMN1; SMN2 | |
| SCHEMBL9753996 | 0.82 | CNR2 (0.47) | CNR2TSHRKEAP1ANPEPERAP1 | |
| SCHEMBL3710024 | 0.80 | TSHR (0.64) | CNR2TSHRKEAP1SMN1; SMN2MEN1 | |
| SCHEMBL341788 | 0.79 | ANPEP (0.52) | MMP8CNR2TSHRKEAP1ANPEP | |
| SCHEMBL6695161 | 0.79 | ALDH1A1 (0.55) | MMP8CNR2TSHRKEAP1ANPEP | |
| SCHEMBL1586317 | 0.78 | MDM2 (0.61) | MMP8KEAP1ALDH1A1 | |
| SCHEMBL9264377 | 0.78 | ANPEP (0.50) | MMP8CNR2TSHRKEAP1ANPEP | |
| SCHEMBL8534054 | 0.78 | MMP8 (0.50) | MMP8CNR2TSHRKEAP1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107986982-A | A kind of method for preparing Primidone impurity A | 精华制药集团南通有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-107986982-A | A kind of method for preparing Primidone impurity A | 精华制药集团南通有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107986982-A | A kind of method for preparing Primidone impurity A | 精华制药集团南通有限公司 | 2018-05-04 | — | — | CN | disclosed |