SCHEMBL28213625

SCHEMBL28213625

COc1cc[c]cc1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.41
ALDH1A1 P00352 1/20 0.37
HIF1A Q16665 1/20 0.37
TDO2 P48775 1/20 0.36
TP53 P04637 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
LMNA P02545 1/20 0.35
DGAT1 O75907 1/20 0.34
MAPT P10636 4/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
EGFR P00533 1/20 0.32
GRIN2C Q14957 1/20 0.32
CASR P41180 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5782738 0.87 KIF11 (0.37) KIF11ALDH1A1HIF1ATDO2TP53
SCHEMBL1644788 0.81 ABL1 (0.42) ALDH1A1TP53SMN1; SMN2MAPTKMT2A
SCHEMBL5468607 0.79 MGAM (0.47) ALDH1A1MAPTMEN1KMT2A
SCHEMBL695241 0.79 MAOA (0.42) ALDH1A1TP53SMN1; SMN2NPC1RAB9A
SCHEMBL27630759 0.76 TLR8 (0.42) TP53SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL5468395 0.76 PDE4A (0.46) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL19692823 0.75 HRH3 (0.41)
SCHEMBL10145033 0.75 ALDH1A1 (0.52) ALDH1A1HIF1AMAPTNPSR1MEN1
SCHEMBL4364262 0.75 KIF11 (0.39) KIF11TP53SMN1; SMN2NPC1RAB9A
SCHEMBL19692830 0.73 MAOB (0.50) LMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110312954-B Phosphor sheet, LED chip and LED package using same, method for manufacturing LED package, and light-emitting device, backlight module, and display each including LED package 东丽株式会社 2021-10-22 CN disclosed
CN-107995920-B Phosphor composition, phosphor sheet, and article formed using same, LED chip, LED package, light-emitting device, and backlight unit 东丽株式会社 2021-03-12 CN disclosed
CN-110312954-A Fluorophor sheet material uses its LED chip and LED encapsulation piece, the manufacturing method of LED encapsulation piece and light emitting device, backlight module and display comprising LED encapsulation piece 东丽株式会社 2019-10-08 CN disclosed
CN-107995920-A Fluorescencer composition, fluorophor sheet material and the manufacture method using their formation, LED chip, LED package, light-emitting device, back light unit, display and LED package 东丽株式会社 2018-05-04 CN disclosed