Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257811 | 0.85 | MAPT (0.41) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL27357774 | 0.85 | MAPT (0.41) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL27502925 | 0.84 | MGLL (0.42) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL27532791 | 0.84 | KMT2A (0.43) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL27375786 | 0.84 | LMNA (0.47) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL27182663 | 0.83 | PRSS1 (0.44) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL28174636 | 0.82 | PRSS1 (0.43) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL28199148 | 0.82 | PRSS1 (0.43) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL28249251 | 0.82 | PRSS1 (0.43) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL28753675 | 0.81 | SMN1; SMN2 (0.47) | KMT2AALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698991-A | 2-oxoindole compound | 凯莫森特里克斯股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-108026050-A | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | 格兰马克药品股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-108026039-A | New carbocyclic compound as ROR gamma modulators | 格兰马克药品股份有限公司 | 2018-05-11 | — | — | CN | disclosed |