Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967770 | 0.84 | POLB (0.36) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL9110139 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2CYP2C19HSD17B10ACE | |
| SCHEMBL27146149 | 0.83 | POLB (0.43) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL27146148 | 0.83 | POLB (0.43) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL1530965 | 0.81 | SMN1; SMN2 (0.46) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL4491733 | 0.81 | SMN1; SMN2 (0.46) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL1031700 | 0.81 | SMN1; SMN2 (0.46) | POLBSPHK1SCN3ALMNAMAOA | |
| Acetic Acid SCHEMBL2183485 | 0.80 | SMN1; SMN2 (0.42) | POLBSPHK1SCN3ALMNAMAOA | |
| SCHEMBL28794057 | 0.80 | BCHE (0.40) | POLBLMNASMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL14311856 | 0.79 | SMN1; SMN2 (0.44) | POLBSPHK1SCN3ALMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026105-A | Tgf beta receptor antagonists | 百时美施贵宝公司 | 2018-05-11 | — | — | CN | disclosed |