Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 8/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177821 | 0.89 | LMNA (0.46) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL20326757 | 0.85 | LMNA (0.44) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL472181 | 0.84 | ACE (0.45) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL472180 | 0.84 | ACE (0.45) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL28214652 | 0.83 | POLB (0.39) | LMNAHSD17B10CYP2C19ACESMN1; SMN2 | |
| SCHEMBL6020595 | 0.81 | CYP2C19 (0.42) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL8935820 | 0.81 | CYP2C19 (0.42) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL8283493 | 0.80 | SMN1; SMN2 (0.45) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL10880904 | 0.80 | SMN1; SMN2 (0.45) | LMNAHSD17B10CYP2C19ACEREN | |
| SCHEMBL151570 | 0.80 | ALDH1A1 (0.47) | LMNAHSD17B10CYP2C19ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065874-C | Novel peptides, the preparation and use thereof | BASF AG (DE) | 2001-05-16 | — | — | CN | disclosed |
| EP-0598899-A4 | LIQUID PHASE SYNTHESIS OF PEPTIDES AND PEPTIDE DERIVATIVES. | SIWRUK GARY A (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0598899-A1 | LIQUID PHASE SYNTHESIS OF PEPTIDES AND PEPTIDE DERIVATIVES | SIWRUK, Gary A. (US) | 1994-06-01 | — | — | EP | disclosed |
| WO-1993025571-A1 | LIQUID PHASE SYNTHESIS OF PEPTIDES AND PEPTIDE DERIVATIVES | SIWRUK GARY A (US) | 1993-12-23 | — | — | WO | disclosed |