SCHEMBL28214751

SCHEMBL28214751

C#COCc1ccccc1.c1cc2cc-2c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AGXT P21549 4/20 0.47
TSHR P16473 1/20 0.41
MGLL Q99685 1/20 0.41
IDO1 P14902 3/20 0.39
NAAA Q02083 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
FFAR1 O14842 1/20 0.37
MAOB P27338 3/20 0.37
NR4A2 P43354 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
PTGER1 P34995 1/20 0.36
PTGER4 P35408 1/20 0.36
PTGER3 P43115 1/20 0.36
PTGER2 P43116 1/20 0.36
ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28561739 0.88 TSHR (0.52) AGXTTSHRIDO1MAOB
SCHEMBL1122448 0.88 TSHR (0.52) AGXTTSHRIDO1MAOB
SCHEMBL27851510 0.86 AGXT (0.47) AGXTTSHRIDO1NAAAMAOB
SCHEMBL10505233 0.73 LTA4H (0.52) TSHRNAAAFFAR1
SCHEMBL5540731 0.72 AGXT (0.59) AGXTMGLLNAAAFFAR1NR4A2
SCHEMBL1573477 0.71 TSHR (0.54) AGXTTSHRIDO1NAAA
SCHEMBL2798157 0.69 TSHR (0.57) AGXTTSHRIDO1MAOB
SCHEMBL379281 0.68 MAOB (0.67) MAOBNR4A2MRGPRX4
Benzylamine SCHEMBL11416949 0.68 LOXL2 (0.74) AGXTTSHRMAOBENPP2
SCHEMBL29187621 0.68 MAOA (0.54) AGXTMGLLMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178741-B β-alkynes seleno alcohols organic compound synthetic method 温州大学苍南研究院 2019-10-22 CN disclosed
CN-108178741-A The synthetic method of β-alkynes seleno alcohols organic compound 温州大学苍南研究院 2018-06-19 CN disclosed