Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214165 | 0.86 | MET (0.45) | HDAC6TLR7BRD4LMNAHTT | |
| SCHEMBL28214100 | 0.77 | HTT (0.48) | LMNAHTTTSHR | |
| SCHEMBL28214711 | 0.74 | YTHDC1 (0.47) | — | |
| SCHEMBL28214704 | 0.73 | MEN1 (0.42) | LMNATSHR | |
| SCHEMBL28214163 | 0.73 | CNR2 (0.43) | — | |
| SCHEMBL28214101 | 0.72 | CNR2 (0.36) | LMNATSHRUSP1 | |
| SCHEMBL7491638 | 0.71 | PDE4A (0.58) | TLR7 | |
| SCHEMBL28214705 | 0.71 | YTHDC1 (0.42) | TLR7LMNAHTTTSHRNPSR1 | |
| SCHEMBL23764023 | 0.70 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL6945092 | 0.69 | HDAC6 (0.64) | HDAC6LMNAHTTSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209466-B | purine derivatives as CB2 receptor agonists | 豪夫迈·罗氏有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-105209466-B | purine derivatives as CB2 receptor agonists | 豪夫迈·罗氏有限公司 | 2018-05-18 | — | — | CN | disclosed |