Ethylene

Ethylene

SCHEMBL28215210

C=C.CC(=O)c1ccoc1C=O

nearest known ligand 0.36

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KMT2A Q03164 3/20 0.33
POLB P06746 2/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
ESR2 Q92731 1/20 0.32
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30671962 0.96 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
Acetic Acid SCHEMBL10454970 0.81 KMT2A (0.32) KMT2ANPC1PKMRAB9ATSHR
SCHEMBL548142 0.78 KMT2A (0.40) KMT2APOLBSMN1; SMN2
SCHEMBL27446996 0.77 RAB9A (0.36) KMT2APOLBNPC1PKMRAB9A
SCHEMBL6051721 0.76
SCHEMBL7475016 0.76 HSP90AB1 (0.38) KMT2APOLBNPC1RAB9ASMN1; SMN2
SCHEMBL7228617 0.76 ALDH1A1 (0.43) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL12477263 0.73
SCHEMBL11776687 0.72 TSHR (0.31) TSHR
SCHEMBL8566976 0.72 ATR (0.34) KMT2ANPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107973735-A A kind of preparation method of N- ethyl-2-aminomethylpentazaneands 江苏康恒化工有限公司 2018-05-01 CN claimed