Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL8437178 | 0.88 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AATM | |
| Styrene SCHEMBL607743 | 0.83 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| Benzene SCHEMBL27612258 | 0.83 | MEN1 (0.64) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2229188 | 0.83 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL27789592 | 0.83 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2821529 | 0.82 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AATM | |
| Propene SCHEMBL10540057 | 0.81 | MEN1 (0.56) | NPC1RAB9AMEN1KMT2AATM | |
| Methyl Alcohol SCHEMBL28009509 | 0.81 | RAB9A (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9359592 | 0.81 | MEN1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL15193 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674283-A | Implantable ophthalmic lens, a method of manufacturing same and a mold for carrying out said method | REPLICATION MEDICAL, INC., A CORPORATION OF DELAWARE | 1997-10-07 | — | — | US | disclosed |