Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579731 | 0.82 | ALDH1A1 (0.59) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL28215323 | 0.80 | KDM4E (0.47) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL27612477 | 0.73 | CA1 (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18579521 | 0.71 | ALDH1A1 (0.56) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL22173643 | 0.69 | KMT2A (0.55) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL30663604 | 0.69 | KMT2A (0.55) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL17101064 | 0.69 | KDR (0.49) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL27580045 | 0.68 | NPC1 (0.59) | KDM4ENPC1MITFRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9488289 | 0.68 | RAD52 (0.62) | KDM4ENPC1MITFTHRBMAPK1 | |
| SCHEMBL16098600 | 0.68 | GSTO1 (0.48) | KDM4ENPC1MITFTHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025189-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2018-05-11 | — | — | CN | disclosed |