Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 4/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856658 | 0.89 | SYK (0.53) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL17712563 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL28049606 | 0.79 | SYK (0.57) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL156401 | 0.79 | SYK (0.50) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL6445371 | 0.79 | KCNH2 (0.67) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL28153213 | 0.79 | KDM4E (0.53) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL24089573 | 0.78 | SYK (0.49) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL24089571 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL26580976 | 0.77 | KDM4E (0.51) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 | |
| SCHEMBL9719821 | 0.77 | SYK (0.58) | SMN1; SMN2KDM4EALDH1A1SYKPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263490-B | Substituted triazolopyridines and methods of use | 基因泰克公司 | 2018-05-22 | — | — | CN | disclosed |