Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163107 | 0.81 | LOXL2 (0.46) | KMOSMYD3TSHR | |
| SCHEMBL28037642 | 0.80 | NPC1 (0.40) | KMOOPRM1OPRD1SMYD3CHRNB2 | |
| SCHEMBL2822690 | 0.78 | ATM (0.46) | KMOSMYD3ATMTSHR | |
| SCHEMBL2822693 | 0.78 | ATM (0.46) | KMOSMYD3ATMTSHR | |
| SCHEMBL2825586 | 0.78 | ATM (0.46) | KMOSMYD3ATMTSHR | |
| SCHEMBL32677547 | 0.70 | SLC7A5 (0.45) | KMOOPRM1OPRD1SMYD3SLC7A5 | |
| SCHEMBL32677546 | 0.70 | SLC7A5 (0.45) | KMOOPRM1OPRD1SMYD3SLC7A5 | |
| SCHEMBL7557139 | 0.69 | LMNA (0.67) | LMNATSHR | |
| SCHEMBL5001045 | 0.69 | ATM (0.47) | KMOATM | |
| SCHEMBL27728458 | 0.69 | ATM (0.47) | KMOATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051037-B | Sphingosine-1-phosphate receptor agonists, method for the preparation thereof and pharmaceutical compositions comprising the same as active agent | LG化学株式会社 | 2018-05-18 | — | — | CN | disclosed |