Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933287 | 0.87 | KMO (0.54) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL28215576 | 0.81 | KMO (0.36) | KMOTSHRSMYD3 | |
| SCHEMBL25883849 | 0.81 | LOXL2 (0.43) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL26154174 | 0.81 | KMO (0.59) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL8414748 | 0.81 | KMO (0.64) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL28037642 | 0.80 | NPC1 (0.40) | KMOKDM1ASMYD3CA12CA1 | |
| SCHEMBL1787841 | 0.80 | KMO (0.67) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL24586212 | 0.80 | LOXL2 (0.46) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL14562482 | 0.80 | GAA (0.47) | LOXL2ALDH1A1HPGDKMOKDM4E | |
| SCHEMBL17710246 | 0.79 | PARP1 (0.45) | LOXL2ALDH1A1HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655680-B | Hormone receptor modulators for the treatment of metabolic mutations and fibrotic conditions and disorders | 阿德利克斯股份有限公司 | 2024-03-05 | — | — | CN | disclosed |