SCHEMBL28215732

SCHEMBL28215732

Cc1c(Cl)ccc2nc3ccccc3cc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
GLA P06280 3/20 0.49
GAA P10253 2/20 0.49
LMNA P02545 2/20 0.49
KMT2A Q03164 2/20 0.49
NPC1 O15118 1/20 0.49
POLB P06746 1/20 0.49
PTBP1 P26599 1/20 0.49
RAB9A P51151 1/20 0.49
RCE1 Q9Y256 1/20 0.49
MAPT P10636 2/20 0.48
ACHE P22303 1/20 0.48
MAOA P21397 2/20 0.44
MAOB P27338 1/20 0.44
PDE10A Q9Y233 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
STAT3 P40763 1/20 0.42
NQO2 P16083 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5387138 0.81 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL2773901 0.81 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL30164507 0.81 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGLAGAA
Bromide SCHEMBL17508351 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL29033070 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDGLAGAA
Iodide SCHEMBL3905318 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL4299906 0.78 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL27869747 0.77 ESR1 (0.57) ALDH1A1KDM4EHPGDGLAGAA
Biphenyl SCHEMBL28506015 0.77 PDE10A (0.54) ALDH1A1KDM4EHPGDGLAGAA
SCHEMBL4160733 0.77 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107973749-A Nitrogen anthracene compound and its synthetic method and application 华东师范大学 2018-05-01 CN claimed
CN-107973749-A Nitrogen anthracene compound and its synthetic method and application 华东师范大学 2018-05-01 CN disclosed