SCHEMBL4160733

SCHEMBL4160733

Clc1cccc2nc3ccccc3cc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
GLA P06280 4/20 0.60
KMT2A Q03164 4/20 0.60
KDM4E B2RXH2 3/20 0.60
GAA P10253 3/20 0.60
HPGD P15428 2/20 0.60
NPC1 O15118 1/20 0.60
LMNA P02545 1/20 0.60
POLB P06746 1/20 0.60
PTBP1 P26599 1/20 0.60
RAB9A P51151 1/20 0.60
RCE1 Q9Y256 1/20 0.60
MAPT P10636 4/20 0.56
ACHE P22303 1/20 0.56
CYP1A2 P05177 2/20 0.52
CYP2A6 P11509 2/20 0.52
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28854322 0.85 ALDH1A1 (0.54) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL5387138 0.80 ALDH1A1 (0.52) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL4299906 0.80 ALDH1A1 (0.70) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL4014126 0.78 KMT2A (0.64) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL28215732 0.77 ALDH1A1 (0.49) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL27961721 0.77 MAPT (0.59) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL11048480 0.77 HTR3A (0.55) ALDH1A1GLAKMT2AKDM4EGAA
Acridine SCHEMBL27603600 0.77 ALDH1A1 (0.94) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL17549872 0.76 PDE3B (0.45) ALDH1A1GLAKMT2AKDM4EGAA
SCHEMBL30857473 0.76 ALDH1A1 (0.64) ALDH1A1GLAKMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104327064-B Acridine-1,3,4-oxadiazole compound having anti-tumor activity, preparation method and uses thereof 广西中医药大学 2017-01-11 CN claimed
EP-0397474-A2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 1990-11-14 EP claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-110114376-B Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2022-06-14 CN disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
CN-108419438-B Coloring composition 株式会社艾迪科 2021-10-01 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111566173-A Coating composition, method for curing the composition, barrier film, and method for producing cured product 株式会社艾迪科 2020-08-21 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
CN-110114376-A Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2019-08-09 CN disclosed
EP-0397474-A2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 1990-11-14 EP disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
EP-0073155-B1 COMPOUNDS HAVING ANTITUMOUR ACTIVITY WARNER-LAMBERT COMPANY (US) 1986-10-29 EP disclosed
US-4537729-A ANTITUMOR AGENTS DEVELOPMENT OF FINANCE CORPORATION OF NEW ZEALAND (NZ) 1985-08-27 US disclosed
US-4479000-A ANTITUMOR AGENTS DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1984-10-23 US disclosed
US-4472582-A 3,5-Disubstituted-4'-(9-acridinylamino)-methane-sulfon-m-anisidide compounds having antitumor properties DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1984-09-18 US disclosed
EP-0025705-B1 COMPOUNDS HAVING ANTITUMOUR PROPERTIES, PROCESS FOR THEIR PREPARATION, THESE COMPOUNDS FOR USE AS ANTITUMOUR AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1983-06-22 EP disclosed
EP-0073155-A2 Compounds having antitumour activity WARNER-LAMBERT COMPANY (US) 1983-03-02 EP disclosed
EP-0025705-A1 Compounds having antitumour properties, process for their preparation, these compounds for use as antitumour agents and pharmaceutical compositions containing them DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1981-03-25 EP disclosed