Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215937 | 0.68 | EPHX2 (0.42) | ALDH1A1POLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL28216507 | 0.67 | KCNH2 (0.42) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL11681422 | 0.64 | HTT (0.55) | MITFALDH1A1HSP90AA1HTTATM | |
| SCHEMBL1133114 | 0.63 | ATM (0.71) | ALDH1A1ATMNPC1RAB9A | |
| SCHEMBL31514279 | 0.63 | ATM (0.71) | ALDH1A1ATMNPC1RAB9A | |
| SCHEMBL11861114 | 0.63 | ALDH1A1 (0.51) | KCNMA1MITFALDH1A1HSP90AA1HTT | |
| SCHEMBL27678726 | 0.63 | OPRK1 (0.46) | ALDH1A1HTTNPSR1POLBDRD2 | |
| Ammonia Solution, Strong SCHEMBL28227232 | 0.62 | ATM (0.68) | ALDH1A1ATMNPC1RAB9A | |
| SCHEMBL50462 | 0.61 | SRD5A2 (0.74) | ALDH1A1ATMMAPTMEN1RAB9A | |
| SCHEMBL9442387 | 0.61 | SRD5A2 (0.74) | ALDH1A1ATMMAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033922-A | A kind of preparation method of 3- acyl groups quinokysalines derivative | 河南工业大学 | 2018-05-15 | — | — | CN | disclosed |